TNFRSF17 (Human) Recombinant Protein
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Result of activity analysis
Result of activity analysis
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Specification
Product Description
Human TNFRSF17 (NP_001183.2, 1 a.a. - 54 a.a.) partial recombinant protein with a Fc, 6×His tag at the C-terminus expressed in HEK293 cells.
Host
Human
Form
Lyophilized
Preparation Method
Mammalian cell (HEK293) expression system
Purification
Ni-sepharose purification
Purity
> 92% (determined by SDS-PAGE)
Endotoxin Level
< 0.1 EU/ug of protein (determined by LAL method)
Activity
Measured by the binding ability in a functional ELISA. Immobilized recombinant human TNFSF13B at 5 ug/mL (100 uL/well) can bind recombinant human TNFRSF17 with a linear range of 3-20 ng/mL.
Quality Control Testing
SDS-PAGE Stained with Coomassie Blue
Recommend Usage
SDS-PAGE
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from a 0.22 um filtered solution of PBS, pH 7.4.
Storage Instruction
Store at -80°C on dry atmosphere, lyophilized antibodies are stable at least 2 years.
After reconstitution with deionized water, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.Note
Result of activity analysis
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Applications
SDS-PAGE
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Gene Info — TNFRSF17
Entrez GeneID
608Protein Accession#
Q02223Gene Name
TNFRSF17
Gene Alias
BCM, BCMA, CD269
Gene Description
tumor necrosis factor receptor superfamily, member 17
Omim ID
109545Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. [provided by RefSeq
Other Designations
B cell maturation antigen|B-cell maturation factor|OTTHUMP00000160261
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