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Last updated: 2022/5/22

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PDCD1 (Human) Recombinant Protein BioActive

  • Catalog # : P6733
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  • Specification
  • Product Description:
  • Human PDCD1 (Q8IX89, 25 a.a. - 167 a.a.) partial recombinant protein with 6xHis tag at C-terminal expressed in HEK293 cells.
  • Host:
  • Human
  • Form:
  • Lyophlized
  • Preparation Method:
  • Mammalian cell (HEK293) expression system
  • Purification:
  • Ni-sepharose purification
  • Purity:
  • > 95% by SDS-PAGE.
  • Endotoxin Level:
  • < 0.1 EU/ug of the protein by LAL method.
  • Activity:
  • Immobilized PDCD1 (Human) Recombinant Protein (Cat # P6733) at 0.5 ug/mL (100 uL/well), dose response curve for Anti-PD1 Ab (BMS) with the ECsub>50 of 57 ng/mL determined by ELISA.
  • Quality Control Testing:
  • SDS-PAGE Stained with Coomassie Blue

    QC Testing of P6733
    This protein was determined by SDS-PAGE with Coomassie Blue, showing a band at 35-55 kDa.
  • Recommend Usage:
  • SDS-PAGE
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • Lyophilized from 0.22 um filtered solution of PBS, pH 7.4.
  • Storage Instruction:
  • Store the lyophilized protein at -20°C to -80°C for long term.
    After reconstitution with a concentration of 0.1-0.5 mg/mL in sterile distilled water, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • Result of bioactivity analysis

  • Immobilized PDCD1 (Human) Recombinant Protein (Cat # P6733) at 0.5 ug/mL (100 uL/well), dose response curve for Anti-PD1 Ab (BMS) with the ECsub>50 of 57 ng/mL determined by ELISA.


  • Applications
  • SDS-PAGE
  • Application Image
  • SDS-PAGE
  • Gene Information
  • Entrez GeneID:
  • 5133
  • Gene Name:
  • PDCD1
  • Gene Alias:
  • CD279,PD1,SLEB2,hPD-1,hPD-l
  • Gene Description:
  • programmed cell death 1
  • Gene Summary:
  • This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq
  • Other Designations:
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