ACE2 (Human) Recombinant Protein
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Result of bioactivity analysis
Result of bioactivity analysis
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Specification
Product Description
Human ACE2 (Q9BYF1, 18 a.a.- 740 a.a.) partial recombinant protein with C-terminal His tag expressed in HEK293 cells.
Host
Human
Theoretical MW (kDa)
84.63
Reactivity
Viruses
Form
Liquid
Preparation Method
Mammalian cell (HEK293) expression system
Purification
Affinity purification
Purity
> 95% by SDS-PAGE
Endotoxin Level
< 0.1 ng/ug (1 EU/ug) as determined by LAL test.
Activity
Immobilized ACE2 (Human) Recombinant Protein (Cat # P6663) at 10 ug/mL (100 uL/well) can bind S1 (SARS-CoV-2) RBD Recombinant Protein. The EC50 of S1 (SARS-CoV-2) RBD Recombinant Protein is 62 ng/mL.
Recommend Usage
Immunogen
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2.
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
Result of bioactivity analysis
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Applications
SDS-PAGE
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Gene Info — ACE2
Entrez GeneID
59272Protein Accession#
Q9BYF1Gene Name
ACE2
Gene Alias
ACEH, DKFZp434A014
Gene Description
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
Omim ID
300335Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63. [provided by RefSeq
Other Designations
ACE-related carboxypeptidase|OTTHUMP00000022963|angiotensin I converting enzyme 2|angiotensin converting enzyme-like protein
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Interactome
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