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Last updated: 2020/8/2

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ACE2 (Human) Recombinant Protein 

  • Catalog # : P6639
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  • Specification
  • Product Description:
  • Human ACE2 (Q9BYF1, 18 a.a. - 740 a.a.) partial recombinant protein with His-Avi tag at C-terminal expressed in HEK293 cells.
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 86.2
  • Form:
  • Liquid
  • Preparation Method:
  • Mammalian cell (HEK293) expression system
  • Purification:
  • Affinity purification
  • Purity:
  • > 95% by SDS-PAGE.
  • Endotoxin Level:
  • < 1.0 EU/ug of the protein by LAL method.
  • Activity:
  • Measured by its binding ability in a functional ELISA. Immobilized ACE2 (Human) Recombinant Protein at 2 ug/mL (100 uL/well) can bind recombinant 2019-nCoV Spike S1 with a linear range of 1.5-104.5 ng/mL.
  • Quality Control Testing:
  • SDS-PAGE Stained with Coomassie Blue

    QC Testing of P6639
    This protein was determined by SDS-PAGE with Coomassie Blue, showing a band at 95-110 kDa.
  • Storage Buffer:
  • In PBS, pH 7.4.
  • Storage Instruction:
  • Store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • Result of bioactivity analysis

  • Applications
  • SDS-PAGE
  • Application Image
  • SDS-PAGE
  • Gene Information
  • Gene Name:
  • ACE2
  • Gene Alias:
  • ACEH,DKFZp434A014
  • Gene Description:
  • angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
  • Gene Summary:
  • The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63. [provided by RefSeq
  • Other Designations:
  • ACE-related carboxypeptidase,OTTHUMP00000022963,angiotensin I converting enzyme 2,angiotensin converting enzyme-like protein
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