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Last updated: 2019/12/1

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BTK (Human) Recombinant Protein BioActive

  • Catalog # : P6472
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  • Specification
  • Product Description:
  • Human BTK (NP_000052, 2 a.a. - 659 a.a.) partial recombinant protein with GST-tag at N-terminal using baculovirus expression system.
  • Host:
  • Viruses
  • Form:
  • Liquid
  • Preparation Method:
  • Baculovirus expression system.
  • Purification:
  • Glutathione sepharose chromatography.
  • Purity:
  • 85%
  • Activity:
  • The activity was measured by off-chip mobility shift assay. The enzyme was incubated with fluorecence-labeled substrate and Mg (or Mn)/ATP. Substrate: Srctide, ATP: 100 uM.
  • Quality Control Testing:
  • The purity was assessed by SDS-PAGE/CBB staining.
  • Storage Buffer:
  • 50 mM Tris-HCl, 150 mM NaCl, 0.05% Brij35, 1 mM DTT, 10% glycerol, pH7.5
  • Storage Instruction:
  • Stored at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • Result of activity analysis

  • Applications
  • Functional Study
  • Application Image
  • Functional Study
  • Gene Information
  • Entrez GeneID:
  • 695
  • Gene Name:
  • BTK
  • Gene Alias:
  • AGMX1,AT,ATK,BPK,IMD1,MGC126261,MGC126262,PSCTK1,XLA
  • Gene Description:
  • Bruton agammaglobulinemia tyrosine kinase
  • Gene Summary:
  • The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. [provided by RefSeq
  • Other Designations:
  • B-cell progenitor kinase,Bruton tyrosine kinase,OTTHUMP00000023676,OTTHUMP00000063593,agammaglobulinemia tyrosine kinase,dominant-negative kinase-deficient Brutons tyrosine kinase,tyrosine-protein kinase BTK
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