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Last updated: 2019/8/18

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INHBA (Human/Mouse/Rat) Recombinant Protein BioActive

  • Catalog # : P6457
  • Visit Frequency :
  • Countries :
  • Specification
  • Product Description:
  • Human/Mouse/Rat INHBA (P08476/Q04998/P18331) recombinant protein expressed in E.Coli.
  • Sequence:
  • MGLECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS
  • Host:
  • Escherichia coli
  • Theoretical MW (kDa):
  • 13.1/26.2
  • Form:
  • Lyophilized
  • Preparation Method:
  • This product is produced with no animal or human origin raw products. All processing and handling employs animal free equipment and animal free protocols.
  • Purity:
  • ≥ 95%
  • Endotoxin Level:
  • ≤ 1 EUs/ug (Kinetic LAL)
  • Activity:
  • ED50 ≤ 10 ng/mL
    Cytotoxicity of MPC-11 cells

    The values provided above are minimum expected values to pass internal requirements.
  • Quality Control Testing:
  • Reducing and Non-Reducing SDS PAGE
  • Storage Buffer:
  • Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA).
  • Storage Instruction:
  • Stored at -20°C to-80°C for 12 month.
    After reconstitution with sterile water at 0.1 mg/mL, store at -20°C to -80°C for 3 months, store at 4°C for 1 month.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • Result of activity analysis

  • Conformation:
  • Dimer
  • Applications
  • Western Blot
  • Functional Study
  • Application Image
  • Western Blot
  • Functional Study
  • Gene Information
  • Entrez GeneID:
  • 3624
  • Protein Accession#:
  • P08476;Q04998;P18331
  • Gene Name:
  • INHBA
  • Gene Alias:
  • EDF,FRP
  • Gene Description:
  • inhibin, beta A
  • Gene Summary:
  • The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta A subunit forms a homodimer, activin A, and also joins with a beta B subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. Finally, it has been shown that the beta A subunit mRNA is identical to the erythroid differentiation factor subunit mRNA and that only one gene for this mRNA exists in the human genome. [provided by RefSeq
  • Other Designations:
  • FSH-releasing protein,Inhibin, beta-1,erythroid differentiation factor,follicle-stimulating hormone-releasing protein,inhibin beta A,inhibin, beta A (activin A, activin AB alpha polypeptide)
  • Gene Information
  • Protein Accession#:
  • P08476;Q04998;P18331
  • Gene Name:
  • Inhba
  • Gene Alias:
  • -
  • Gene Description:
  • inhibin beta-A
  • Other Designations:
  • activin,inhibin beta A
  • Gene Information
  • Protein Accession#:
  • P08476;Q04998;P18331
  • Gene Name:
  • Inhba
  • Gene Alias:
  • -
  • Gene Description:
  • inhibin beta-A
  • Other Designations:
  • activin A,inhibin beta A
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