CCL27 (Human) Recombinant Protein
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Specification
Product Description
Human CCL27 (Q9Y4X3) recombinant protein expressed in E. Coli.
Sequence
FLLPPSTACCTQLYRKPLSDKLLRKVIQVELQEADGDCHLQAFVLHLAQRSICIHPQNPSLSQWFEHQERKLHGTLPKLNFGMLRKMG
Host
Escherichia coli
Theoretical MW (kDa)
10
Form
Lyophilized
Purity
> 95%
Endotoxin Level
<= 1 EUs/ug (LAL gel clot method)
Activity
Determined by the ability to chemoattract CXCR3 transfected cells using a concentration of 10-100 ng/mL.
Storage Buffer
Lyophilized from PBS, pH 7.2.
Storage Instruction
Stored at -20°C to-80°C.
After reconstitution with sterile water not less than 0.1 mg/mL, store at -20°C to -80°C for 6 months, store at 4°C for 1 month.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot
Functional Study
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Gene Info — CCL27
Entrez GeneID
10850Protein Accession#
Q9Y4X3Gene Name
CCL27
Gene Alias
ALP, CTACK, CTAK, ESKINE, ILC, PESKY, SCYA27
Gene Description
chemokine (C-C motif) ligand 27
Omim ID
604833Gene Ontology
HyperlinkGene Summary
This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene is chemotactic for skin-associated memory T lymphocytes. This cytokine may also play a role in mediating homing of lymphocytes to cutaneous sites. It specifically binds to chemokine receptor 10 (CCR10). Studies of a similar murine protein indicate that these protein-receptor interactions have a pivotal role in T cell-mediated skin inflammation. [provided by RefSeq
Other Designations
CC chemokine ILC|IL-11 Ralpha-locus chemokine|OTTHUMP00000000533|OTTHUMP00000021297|cutaneous T-cell attracting chemokine|skinkine|small inducible cytokine A27|small inducible cytokine subfamily A (Cys-Cys), member 27
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Pathway
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Disease
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