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Last updated: 2019/12/1

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TNFSF8 (Human) Recombinant Protein BioActive

  • Catalog # : P6341
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  • Specification
  • Product Description:
  • Human TNFSF8 (P32971) recombinant protein expressed in HEK293 cells.
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 65
  • Form:
  • Lyophilized
  • Purity:
  • > 97%
  • Endotoxin Level:
  • ≤ 1 EUs/ug (LAL gel clot method)
  • Activity:
  • The activity was tested by the ability of immobilized recombinant human CD30L to bind Human CD30 with a linear range of 300-2000 pg/mL.
  • Storage Buffer:
  • Lyophilized from 0.2 um filtered PBS solution, pH7.2, 5% Trehalose.
  • Storage Instruction:
  • Stored at -20°C to-80°C.
    After reconstitution with sterile water not less than 0.1 mg/mL, store at -20°C to -80°C for 12 months, store at 4°C for 1 month.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Functional Study
  • Application Image
  • Western Blot
  • Functional Study
  • Gene Information
  • Entrez GeneID:
  • 944
  • Gene Name:
  • TNFSF8
  • Gene Alias:
  • CD153,CD30L,CD30LG,MGC138144
  • Gene Description:
  • tumor necrosis factor (ligand) superfamily, member 8
  • Gene Summary:
  • The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF8/CD30, which is a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies. The engagement of this cytokine expressed on B cell surface plays an inhibitory role in modulating Ig class switch. This cytokine was shown to enhance cell proliferation of some lymphoma cell lines, while to induce cell death and reduce cell proliferation of other lymphoma cell lines. The pleiotropic biologic activities of this cytokine on different CD30+ lymphoma cell lines may play a pathophysiologic role in Hodgkin's and some non-Hodgkin's lymphomas. [provided by RefSeq
  • Other Designations:
  • CD153 antigen,CD30 antigen ligand,CD30 ligand,OTTHUMP00000022762
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