GDF11 (Human/Mouse/Rat) Recombinant Protein
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Result of activity analysis
Result of activity analysis
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Specification
Product Description
Human/Mouse/Rat GDF11 (O95390/Q9Z1W4/Q9Z217) recombinant protein expressed in E.Coli.
Sequence
NLGLDCDEHSSESRCCRYPLTVDFEAFGWDWIIAPKRYKANYCSGQCEYMFMQKYPHTHLVQQANPRGSAGPCCTPTKMSPINMLYFNDKQQIIYGKIPGMVVDRCGCS
Host
Escherichia coli
Theoretical MW (kDa)
12.5/24.9
Form
Lyophilized
Preparation Method
This product is produced with no animal or human origin raw products. All processing and handling employs animal free equipment and animal free protocols.
Purity
>= 95%
Endotoxin Level
<= 1 EUs/ug (Kinetic LAL)
Activity
ED50 <= 100 ng/mL
Alkaline phosphatase activity in ATDC5 cells
The values provided above are minimum expected values to pass internal requirements.Quality Control Testing
Reducing and Non-Reducing SDS PAGE
Conformation
Dimer
Storage Buffer
Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA).
Storage Instruction
Stored at -20°C to-80°C for 12 month.
After reconstitution with sterile 10 mM HCl at 0.1 mg/mL, store at -20°C to -80°C for 3 months, store at 4°C for 1 month.
Aliquot to avoid repeated freezing and thawing.Note
Result of activity analysis
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Applications
Western Blot
Functional Study
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Gene Info — GDF11
Entrez GeneID
10220Protein Accession#
O95390;Q9Z1W4;Q9Z217Gene Name
GDF11
Gene Alias
BMP-11, BMP11
Gene Description
growth differentiation factor 11
Omim ID
603936Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in mice and Xenopus suggest that this protein is involved in mesodermal formation and neurogenesis during embryonic development. [provided by RefSeq
Other Designations
bone morphogenetic protein 11
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Gene Info — Gdf11
Entrez GeneID
14561Protein Accession#
O95390;Q9Z1W4;Q9Z217Gene Name
Gdf11
Gene Alias
Bmp11
Gene Description
growth differentiation factor 11
Gene Ontology
HyperlinkOther Designations
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Gene Info — Gdf11
Entrez GeneID
29454Protein Accession#
O95390;Q9Z1W4;Q9Z217Gene Name
Gdf11
Gene Alias
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Gene Description
growth differentiation factor 11
Gene Ontology
HyperlinkOther Designations
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Interactome
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Disease
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