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FGF8 (Human/Mouse) Recombinant Protein BioActive

  • Catalog # : P6318
  • Visit Frequency :
  • Countries :
  • Specification
  • Product Description:
  • Human/Mouse FGF8 (P55075/P37237) recombinant protein expressed in E.Coli.
  • Sequence:
  • MQVTVQSSPNFTQHVREQSLVTDQLSRRLIRTYQLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGAETGLYICMNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYEGWYMAFTRKGRPRKGSKTRQHQREVHFMKRLPRGHHTTEQSLRFEFLNYPPFTRSLRGSQRTWAPEPR
  • Host:
  • Escherichia coli
  • Theoretical MW (kDa):
  • 22.5
  • Form:
  • Lyophilized
  • Preparation Method:
  • This product is produced with no animal or human origin raw products. All processing and handling employs animal free equipment and animal free protocols.
  • Purity:
  • >= 95%
  • Endotoxin Level:
  • <= 1 EUs/ug (Kinetic LAL)
  • Activity:
  • ED50 <= 150 ng/mL
    3T3 cell proliferation

    The values provided above are minimum expected values to pass internal requirements.
  • Quality Control Testing:
  • Reducing and Non-Reducing SDS PAGE
  • Storage Buffer:
  • Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA).
  • Storage Instruction:
  • Stored at -20°C to-80°C for 12 month.
    After reconstitution with sterile water at 0.1 mg/mL, store at -20°C to -80°C for 3 months, store at 4°C for 1 month.
    Aliquot to avoid repeated freezing and thawing.
    If a precipitate is observed, centrifuge the solution thoroughly and use only the soluble fraction (removing it from the precipitate). A 10% overfill has been added to compensate for any loss of protein in the precipitate.
  • Note:
  • Result of activity analysis

  • Conformation:
  • Monomer
  • Applications
  • Western Blot
  • Functional Study
  • Application Image
  • Western Blot
  • Functional Study
  • Gene Information
  • Entrez GeneID:
  • 2253
  • Protein Accession#:
  • P55075;P37237
  • Gene Name:
  • FGF8
  • Gene Alias:
  • AIGF,HBGF-8,MGC149376
  • Gene Description:
  • fibroblast growth factor 8 (androgen-induced)
  • Gene Summary:
  • The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is known to be a factor that supports androgen and anchorage independent growth of mammary tumor cells. Overexpression of this gene has been shown to increase tumor growth and angiogensis. The adult expression of this gene is restricted to testes and ovaries. Temporal and spatial pattern of this gene expression suggests its function as an embryonic epithelial factor. Studies of the mouse and chick homologs revealed roles in midbrain and limb development, organogenesis, embryo gastrulation and left-right axis determination. The alternative splicing of this gene results in four transcript variants. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000020348,OTTHUMP00000020349,OTTHUMP00000020350,OTTHUMP00000020351,androgen-induced growth factor,fibroblast growth factor 8
  • Gene Information
  • Protein Accession#:
  • P55075;P37237
  • Gene Name:
  • Fgf8
  • Gene Alias:
  • Aigf,Fgf-8,MGC59627
  • Gene Description:
  • fibroblast growth factor 8
  • Other Designations:
  • OTTMUSP00000024240
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