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Last updated: 2019/8/18

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BMP4 (Human) Recombinant Protein BioActive

  • Catalog # : P6241
  • Visit Frequency :
  • Countries :
  • Specification
  • Product Description:
  • Human BMP4 (P12644) recombinant protein expressed in CHO cells.
  • Sequence:
  • SPKHHSQRARKKNKNCRRHSLYVDFSDVGWNDWIVAPPGYQAFYCHGDCPFPLADHLNSTNHAIVQTLVNSVNSSIPKACCVPTELSAISMLYLDEYDKVVLKNYQEMVVEGCGCR
  • Host:
  • Hamster
  • Theoretical MW (kDa):
  • 13.1/26.2
  • Form:
  • Lyophilized
  • Purity:
  • ≥ 95%
  • Endotoxin Level:
  • ≤ 1 EUs/ug (Kinetic LAL) (50% confidence)
  • Activity:
  • ED50 ≤ 15 ng/mL
    Alkaline phosphatase activity induced in ATDC-5 cells

    The values provided above are minimum expected values to pass internal requirements.
  • Quality Control Testing:
  • Reducing and Non-Reducing SDS PAGE
  • Storage Buffer:
  • Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA).
  • Storage Instruction:
  • Stored at -20°C to-80°C for 12 month.
    After reconstitution with sterile water at 0.1 mg/mL, store at -20°C to -80°C for 3 months, store at 4°C for 1 month.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • Result of activity analysis

  • Conformation:
  • Dimer
  • Applications
  • Western Blot
  • Functional Study
  • Application Image
  • Western Blot
  • Functional Study
  • Gene Information
  • Entrez GeneID:
  • 652
  • Gene Name:
  • BMP4
  • Gene Alias:
  • BMP2B,BMP2B1,MCOPS6,ZYME
  • Gene Description:
  • bone morphogenetic protein 4
  • Gene Summary:
  • The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein. [provided by RefSeq
  • Other Designations:
  • bone morphogenetic protein 2B
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