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IL2RA (Human) Recombinant proteinBioActive

  • Catalog # : P6152
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  • Specification
  • Product Description:
  • Human IL2RA (P01589) partial recombinant protein expressed in Hi-5 Insect cells.
  • Sequence:
  • ELCDDDPPEIPHATFKAMAYKEGTMLNCECKRGFRRIKSGSLYMLCTGNSSHSSWDNQCQCTSSATRNTTKQVTPQPEEQKERKTTEMQSPMQPVDQASLPGHCREPPPWENEATERIYHFVVGQMVYYQCVQGYRALHRGPAESVCKMTHGKTRWTQPQLICTGEMETSQFPGEEKPQASPEGRPESETSCLVTTTDFQIQTEMAATMETSIFTTEYQ
  • Host:
  • Insect
  • Theoretical MW (kDa):
  • 24.8
  • Reactivity:
  • Human
  • Form:
  • Lyophilized
  • Preparation Method:
  • Insect cell (Hi-5) expression system
  • Purity:
  • 98%
  • Endotoxin Level:
  • Endotoxin level is <0.1 ng/ug of protein (<1 EU/ug).
  • Activity:
  • Determined by its ability to increase the proliferation effect of IL-2 in murine CTLL-2 cells. In the presence of 1 ng/mL of recombinant IL-2, the expected ED50 for this effect is between 0.5-1.5 ug/mL.
  • Recommend Usage:
  • Activity assay
    SDS-PAGE
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • Lyophilized from 1x PBS.
  • Storage Instruction:
  • Store at -20°C.
    Reconstitute in 1x PBS pH 7.2 to a concentration of 0.1- 1.0 mg/mL. Do not vortex.
    For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
  • Applications
  • Functional Study
  • SDS-PAGE
  • Application Image
  • Functional Study
  • SDS-PAGE
  • Gene Information
  • Entrez GeneID:
  • 3559
  • Gene Name:
  • IL2RA
  • Gene Alias:
  • CD25,IDDM10,IL2R,TCGFR
  • Gene Description:
  • interleukin 2 receptor, alpha
  • Gene Summary:
  • The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. [provided by RefSeq
  • Other Designations:
  • Interleukin-2 receptor,OTTHUMP00000019030,OTTHUMP00000044870,interleukin 2 receptor, alpha chain
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