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CXCL11 (Human) Recombinant ProteinBioActive

  • Catalog # : P6103
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  • Specification
  • Product Description:
  • Human CXCL11 (O14625) partial recombinant protein expressed in E. coli.
  • Sequence:
  • FPMFKRGRCLCIGPGVKAVKVADIEKASIMYPSNNCDKIEVIITLKENKGQRCLNPKSKQARLIIKKVERKNF
  • Host:
  • Escherichia coli
  • Theoretical MW (kDa):
  • 8.3
  • Reactivity:
  • Human
  • Form:
  • Lyophilized
  • Preparation Method:
  • E. coli expression system
  • Purity:
  • 98%
  • Endotoxin Level:
  • <0.1 ng/ug (<1 EU/ug)
  • Activity:
  • Determined by its chemoattractivity with IL-2 activated T-cells at the range of 0.1-10.0 ng/ml.
  • Recommend Usage:
  • SDS-PAGE
    Activity assay
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • Lyophilized from solutions contain no sodiun azide nor carrier protein.
  • Storage Instruction:
  • Store at -20°C.
    Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Do not vortex.
    For extended storage, it is recommended to be further diluted in buffer containing carrier protein (e.g. 0.1% BSA) and stored in aliquots at -20°C to -80°C.
  • Applications
  • Functional Study
  • SDS-PAGE
  • Application Image
  • Functional Study
  • SDS-PAGE
  • Gene Information
  • Entrez GeneID:
  • 6373
  • Gene Name:
  • CXCL11
  • Gene Alias:
  • H174,I-TAC,IP-9,IP9,MGC102770,SCYB11,SCYB9B,b-R1
  • Gene Description:
  • chemokine (C-X-C motif) ligand 11
  • Gene Summary:
  • Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC. This gene is a CXC member of the chemokine superfamily. Its encoded protein induces a chemotactic response in activated T-cells and is the dominant ligand for CXC receptor-3. The gene encoding this protein contains 4 exons and at least three polyadenylation signals which might reflect cell-specific regulation of expression. IFN-gamma is a potent inducer of transcription of this gene. [provided by RefSeq
  • Other Designations:
  • small inducible cytokine B11,small inducible cytokine subfamily B (Cys-X-Cys), member 11,small inducible cytokine subfamily B (Cys-X-Cys), member 9B
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