Measured by its ability to induce IL-8 production of human PBMCs.
SDS-PAGE Activity assay The optimal working dilution should be determined by the end user.
Lyophilized from 10mM Sodium Phosphate, pH 7.0 and 50mM NaCl.
Store at -20°C. Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Do not vortex. For extended storage, it is recommended to be further diluted in buffer containing carrier protein (e.g. 0.1% BSA) and stored in aliquots at -20°C to -80°C.
The protein encoded by this gene is a member of the interleukin 1 cytokine family. The activity of this cytokine is mediated by interleukin 1 receptor-like 2 (IL1RL2/IL1R-rp2), and is specifically inhibited by interleukin 1 family, member 5 (IL1F5/IL-1 delta). Interferon-gamma, tumor necrosis factor-alpha and interleukin 1, beta (IL1B) are reported to stimulate the expression of this cytokine in keratinocytes. The expression of this cytokine in keratinocytes can also be induced by a contact hypersensitivity reaction or herpes simplex virus infection. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq
IL-1 related protein 2,IL-1(EPSILON),IL-1-epsilon,interleukin 1-related protein 2,interleukin-1 epsilon,interleukin-1 homolog 1