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Last updated: 2016/11/27

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CCL11 (Human) Recombinant ProteinBioActive

  • Catalog # : P5976
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  • Specification
  • Product Description:
  • Human CCL11 (P51671) partial recombinant protein expressed in Escherichia coli.
  • Sequence:
  • GPASVPTTCCFNLANRKIPLQRLESYRRITSGKCPQKAVIFKTKLAKDICADPKKKWVQDSMKYLDQKSPTPKP
  • Host:
  • Escherichia coli
  • Theoretical MW (kDa):
  • 8.3
  • Reactivity:
  • Bacteria, Guinea pig, Human, Mouse
  • Form:
  • Lyophilized
  • Preparation Method:
  • Escherichia coli expression system
  • Purity:
  • 98%
  • Endotoxin Level:
  • Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug).
  • Activity:
  • Determined by its ability to chemoattract human peripheral blood eosinophils using a concentration range of 0.1-10.0 ng/mL.
  • Recommend Usage:
  • Activity assay
    SDS-PAGE
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • Lyophilized from solutions contain no sodiun azide nor carrier protein
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Functional Study
  • SDS-PAGE
  • Application Image
  • Functional Study
  • SDS-PAGE
  • Gene Information
  • Entrez GeneID:
  • 6356
  • Gene Name:
  • CCL11
  • Gene Alias:
  • MGC22554,SCYA11
  • Gene Description:
  • chemokine (C-C motif) ligand 11
  • Gene Summary:
  • This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil specific chemokine assumed to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections. [provided by RefSeq
  • Other Designations:
  • eosinophil chemotactic protein,eotaxin,small inducible cytokine A11,small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin)
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