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INHBA (Human) Recombinant ProteinBioActive

  • Catalog # : P5925
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  • Specification
  • Product Description:
  • Human INHBA (P08476, 311 a.a. - 426 a.a.) full-length recombinant protein with N-terminal His tag expressed in Nicotiana benthamiana.
  • Sequence:
  • HHHHHHGLECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS
  • Host:
  • Plants
  • Reactivity:
  • Human
  • Form:
  • Lyophilized
  • Preparation Method:
  • Non-transgenic plants (Nicotiana benthamiana) expression system
  • Purification:
  • Sequential chromatography (FPLC)
  • Purity:
  • > 97% by SDS-PAGE
  • Endotoxin Level:
  • < 0.04 EU/ug protein
  • Activity:
  • The biological activity of Activin A is measured by its ability to inhibit mouse plasmacytoma cell line (MPC-11) cells proliferation and induce keratinocytes differentiation.
  • Quality Control Testing:
  • 500 ng/lane in 15% SDS-polyacrylamide gel and stained with Coomassie blue

    QC Testing of P5925
    Several forms are observed with different predicted molecular masses such as monomer (13.7 kDa), dimmer ( 27.4 kDa) and multimeric forms.
  • Storage Buffer:
  • Lyophilized from Tris HCl 0.05M buffer at pH 7.4
  • Storage Instruction:
  • Store at -20°C on dry atmosphere.
    After reconstitution with sterilized water, store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot (Recombinant protein)
  • Western Blot (Recombinant protein)
  • Western blot analysis of INHBA (Human) Recombinant Protein (Cat # P5925) using protein specific antibody. 250 ng/lane of INHBA (Human) Recombinant Protein
  • Functional Study
  • SDS-PAGE
  • Application Image
  • Western Blot (Recombinant protein)
  • Western Blot (Recombinant protein)
  • enlarge
  • Functional Study
  • SDS-PAGE
  • Gene Information
  • Entrez GeneID:
  • 3624
  • Gene Name:
  • INHBA
  • Gene Alias:
  • EDF,FRP
  • Gene Description:
  • inhibin, beta A
  • Gene Summary:
  • The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta A subunit forms a homodimer, activin A, and also joins with a beta B subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. Finally, it has been shown that the beta A subunit mRNA is identical to the erythroid differentiation factor subunit mRNA and that only one gene for this mRNA exists in the human genome. [provided by RefSeq
  • Other Designations:
  • FSH-releasing protein,Inhibin, beta-1,erythroid differentiation factor,follicle-stimulating hormone-releasing protein,inhibin beta A,inhibin, beta A (activin A, activin AB alpha polypeptide)
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