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GP1BA N37O/N175O (Human) Recombinant Protein

  • Catalog # : P5896
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  • Specification
  • Product Description:
  • Human GP1BA (NP_000164, 17 a.a - 306 a.a) partial protein (double sulfated form) with C-terminal hexahistidine tag expressed in HEK293EBNA1 cells.
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 33.5
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Preparation Method:
  • Mammalian cell (HEK293EBNA1) expression system
  • Quality Control Testing:
  • NuPAGE Stained with Coomassie Blue

    QC Testing of P5896
  • Storage Buffer:
  • In PBS without preservative
  • Storage Instruction:
  • Store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Application Image
  • Gene Information
  • Entrez GeneID:
  • 2811
  • Gene Name:
  • GP1BA
  • Gene Alias:
  • BSS,CD42B,CD42b-alpha,GP1B,MGC34595
  • Gene Description:
  • glycoprotein Ib (platelet), alpha polypeptide
  • Gene Summary:
  • Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that are linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Several polymorphisms and mutations have been described in this gene, some of which are the cause of Bernard-Soulier syndromes and platelet-type von Willebrand disease. [provided by RefSeq
  • Other Designations:
  • platelet glycoprotein Ib alpha polypeptide,platelet membrane glycoprotein 1b-alpha subunit
  • Interactome
  • Interactome
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