MBL2 (Human) Recombinant Protein
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Specification
Product Description
Human MBL2 (NP_000233, 21a.a. - 248 a.a.) partial recombinant protein with N-terminal hexahistidine tag and a TEV cleavage site expressed in HEK293EBNA1 cells.
Sequence
GSHHHHHHDYDIPSSENLYFQGSETVTCEDAQKTCPAVIACSSPGINGFPGKDGRDGTKGEKGEPGQGLRGLQGPPGKLGPPGNPGPSGSPGPKGQKGDPGKSPDGDSSLAASERKALQTEMARIKKWLTFSLGKQVGNKTNGEIMTFEKVKALCVKFQASVATPRNAAENGAIQNLIKEEAGITDEKTEGQFVDLTGNRLTYTNWNEGEPNNAGSDEDCVLLLKNGQWNDVPCSTSHLAVCEFPIAAA
Host
Human
Reactivity
Human
Form
Liquid
Preparation Method
Mammalian cell (HEK293EBNA1) expression system
Concentration
175 ug/mL
Quality Control Testing
NuPAGE Stained with Coomassie Blue
Lane1: Non-reduced MBL2, Lane2: Reduced MBL2
Storage Buffer
In PBS without preservative
Storage Instruction
Store at -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
SDS-PAGE
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Gene Info — MBL2
Entrez GeneID
4153GeneBank Accession#
NM_000242Protein Accession#
NP_000233Gene Name
MBL2
Gene Alias
COLEC1, HSMBPC, MBL, MBP, MBP1, MGC116832, MGC116833
Gene Description
mannose-binding lectin (protein C) 2, soluble (opsonic defect)
Omim ID
154545Gene Ontology
HyperlinkGene Summary
This gene encodes the soluble mannose-binding lectin or mannose-binding protein found in serum. The protein encoded belongs to the collectin family and is an important element in the innate immune system. The protein recognizes mannose and N-acetylglucosamine on many microorganisms, and is capable of activating the classical complement pathway. Deficiencies of this gene have been associated with susceptibility to autoimmune and infectious diseases. [provided by RefSeq
Other Designations
OTTHUMP00000019622|mannan-binding lectin|mannose-binding lectin 2, soluble (opsonic defect)|mannose-binding protein C|soluble mannose-binding lectin
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