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Last updated: 2016/12/4

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C2 (Human) Recombinant Protein

  • Catalog # : P5886
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  • Specification
  • Product Description:
  • Human C2 full-length recombinant protein with N-terminal hexahistidine tag expressed in in HEK293 cells.
  • Host:
  • Human
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Preparation Method:
  • Mammalian cell (HEK293) expression system
  • Concentration:
  • 0.4 mg/mL
  • Quality Control Testing:
  • NuPAGE Stained with Coomassie Blue

    QC Testing of P5886
  • Storage Buffer:
  • The enzyme is stored in PBS containing 5 mM benzamidin HCl.
  • Storage Instruction:
  • Store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • SDS-PAGE
  • Application Image
  • SDS-PAGE
  • Gene Information
  • Entrez GeneID:
  • 717
  • Gene Name:
  • C2
  • Gene Alias:
  • CO2,DKFZp779M0311
  • Gene Description:
  • complement component 2
  • Gene Summary:
  • Component C2 is a serum glycoprotein that functions as part of the classical pathway of the complement system. Activated C1 cleaves C2 into C2a and C2b. The serine proteinase C2a then combines with complement factor 4b to create the C3 or C5 convertase. Deficiency of C2 has been reported to associated with certain autoimmune diseases and SNPs in this gene have been associated with altered susceptibility to age-related macular degeneration. This gene localizes within the class III region of the MHC on the short arm of chromosome 6. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described in publications but their full-length sequence has not been determined
  • Other Designations:
  • C3/C5 convertase,OTTHUMP00000029277,OTTHUMP00000062690,complement C2,complement component C2
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