GINS4 (Human) Recombinant Protein
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Specification
Product Description
Human GINS4 (NP_115712, 1 a.a. - 223 a.a.) full-length recombinant protein with His tag expressed in Escherichia coli.
Sequence
MGSSHHHHHHSSGLVPRGSHMTEEVDFLGQDSDGGSEEVVLTPAELIERLEQAWMNEKFAPELLESKPEIVECVMEQLEHMEENLRRAKREDLKVSIHQMEMERIRYVLSSYLRCRLMKIEKFFPHVLEKEKTRPEGEPSSLSPEELAFAREFMANTESYLKNVALKHMPPNLQKVDLFRAVPKPDLDSYVFLRVRERQENILVEPDTDEQRDYVIDLEKGSQHLIRYKTIAPLVASGAVQLI
Host
Escherichia coli
Theoretical MW (kDa)
28.2
Form
Liquid
Preparation Method
Escherichia coli expression system
Purity
> 90% by SDS - PAGE
Quality Control Testing
3 ug/lane in 15% SDS-PAGE Stained with Coomassie Blue. Due to the protein nature, dimmers and multimers may be observed.
Storage Buffer
In 20 mM Tris-HCl buffer, 0.2 M NaCl, pH 8.0 (20% glycerol, 1 mM DTT).
Storage Instruction
Store at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
SDS-PAGE
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Gene Info — GINS4
Entrez GeneID
84296Gene Name
GINS4
Gene Alias
MGC14799, SLD5
Gene Description
GINS complex subunit 4 (Sld5 homolog)
Omim ID
610611Gene Ontology
HyperlinkGene Summary
The yeast heterotetrameric GINS complex is made up of Sld5, Psf1 (GINS1; MIM 610608), Psf2 (GINS2; MIM 610609), and Psf3 (GINS3; MIM 610610). The formation of the GINS complex is essential for the initiation of DNA replication in yeast and Xenopus egg extracts (Ueno et al., 2005 [PubMed 16287864]). See GINS1 for additional information about the GINS complex.[supplied by OMIM
Other Designations
GINS complex subunit 4|SLD5 homolog
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