PTGR1 (Human) Recombinant Protein
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Specification
Product Description
Human PTGR1 (NP_036344, 1 a.a. - 329 a.a. ) full-length recombinant protein with His tag expressed in Escherichia coli.
Sequence
MGSSHHHHHHSSGLVPRGSHMGSEFMVRTKTWTLKKHFVGYPTNSDFELKTAELPPLKNGEVLLEALFLTVDPYMRVAAKRLKEGDTMMGQQVAKVVESKNVALPKGTIVLASPGWTTHSISDGKDLEKLLTEWPDTIPLSLALGTVGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVAYLQKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQMKKFGRIAICGAISTYNRTGPLPPGPPPEIVIYQELRMEAFVVYRWQGDARQKALKDLLKWVLEGKIQYKEYIIEGFENMPAAFMGMLKGDNLGKTIVKA
Host
Escherichia coli
Theoretical MW (kDa)
38.6
Form
Liquid
Preparation Method
Escherichia coli expression system
Purity
> 90% by SDS - PAGE
Quality Control Testing
3 ug/lane in 15% SDS-PAGE Stained with Coomassie Blue. Due to the protein nature, dimmers and multimers may be observed.
Storage Buffer
In 20 mM Tris-HCl buffer, 200 mM NaCl, pH 7.5 (10% glycerol, 1 mM DTT).
Storage Instruction
Store at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
SDS-PAGE
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Gene Info — PTGR1
Entrez GeneID
22949Gene Name
PTGR1
Gene Alias
LTB4DH, MGC34943, ZADH3
Gene Description
prostaglandin reductase 1
Omim ID
601274Gene Ontology
HyperlinkGene Summary
This gene encodes an enzyme that is involved in the inactivation of the chemotactic factor, leukotriene B4. The encoded protein specifically catalyzes the NADP+ dependent conversion of leukotriene B4 to 12-oxo-leukotriene B4. A pseudogene of this gene is found on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq
Other Designations
NADP-dependent leukotriene B4 12-hydroxydehydrogenase|OTTHUMP00000021915|leukotriene B4 12-hydroxydehydrogenase|zinc binding alcohol dehydrogenase domain containing 3
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Interactome
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Disease
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