TXNDC12 (Human) Recombinant Protein
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Specification
Product Description
Human TXNDC12 (NP_056997, 27 a.a. - 172 a.a.) partial recombinant protein with His tag expressed in Escherichia coli.
Sequence
MRGSHHHHHHGMASMTGGQQMGRDLYDDDDKDRWGSHMHNGLGKGFGDHIHWRTLEDGKKEAAASGLPLMVIIHKSWCGACKALKPKFAESTEISELSHNFVMVNLEDEEEPKDEDFSPDGGYIPRILFLDPSGKVHPEIINENGNPSYKYFYVSAEQVVQGMKEAQERLTGDAFRKKHLEDEL
Host
Escherichia coli
Theoretical MW (kDa)
20.8
Form
Liquid
Preparation Method
Escherichia coli expression system
Purity
> 90% by SDS - PAGE
Quality Control Testing
3 ug/lane in 15% SDS-PAGE Stained with Coomassie Blue. Due to the protein nature, dimmers and multimers may be observed.
Storage Buffer
In 20 mM Tris-HCl buffer, 0.15 M NaCl, pH 8.0 (10% glycerol).
Storage Instruction
Store at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
SDS-PAGE
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Gene Info — TXNDC12
Entrez GeneID
51060Gene Name
TXNDC12
Gene Alias
AGR1, ERP18, ERP19, TLP19, hAG-1
Gene Description
thioredoxin domain containing 12 (endoplasmic reticulum)
Omim ID
609448Gene Ontology
HyperlinkGene Summary
TXNDC12 belongs to the thioredoxin superfamily (see TXN; MIM 187700). Members of this superfamily possess a thioredoxin fold with a consensus active-site sequence (CxxC) and have roles in redox regulation, defense against oxidative stress, refolding of disulfide-containing proteins, and regulation of transcription factors (Liu et al., 2003 [PubMed 14557066]).[supplied by OMIM
Other Designations
OTTHUMP00000010300|anterior gradient homolog 1|endoplasmic reticulum thioredoxin superfamily member, 18 kDa|thioredoxin-like protein p19
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