EPHA4 (Human) Recombinant Protein

Catalog # P5705

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Price

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Quantity

Size:5 ug
Price: USD $ 531.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
Images
QC Test

Result of activity analysis
Note

Result of activity analysis

Result of activity analysis

  • Specification

    Product Description

    Human EPHA4 (NP_004430.3, 586 a.a. - 986 a.a.) partial recombinant protein with GST tag expressed in Baculovirus infected Sf21 cells.Bioactive Protein,Bioactive Proteins,Bioactive,Active,Functional Protein,Functional Proteins

    Host

    insect

    Theoretical MW (kDa)

    72

    Form

    Liquid

    Preparation Method

    Baculovirus infected insect cell (Sf21) expression system

    Purification

    Glutathione sepharose chromatography

    Purity

    89 % by SDS-PAGE/CBB staining.

    Activity

    The activity was measured by off-chip mobility shift assay. The enzyme was incubated with fluorescence-labeled substrate and Mg (or Mn)/ATP. The phosphorylated and unphosphorylated substrates were separated and detected by LabChip™3000.
    Substrate : Blk/Lyntide. ATP: 100 µM.

    Quality Control Testing

    Loading 1 ug protein in SDS-PAGE

    Storage Buffer

    In 50 mM Tris-HCl, 150 mM NaCl, pH 7.5 (0.05% Brij35, 1 mM DTT, 10% glycerol)

    Storage Instruction

    Store at -80°C.
    Aliquot to avoid repeated freezing and thawing.

    Note

    Result of activity analysis

  • Applications

    Functional Study

    SDS-PAGE

  • Gene Info — EPHA4

    Entrez GeneID

    2043

    Protein Accession#

    NP_004429.1

    Gene Name

    EPHA4

    Gene Alias

    HEK8, SEK, TYRO1

    Gene Description

    EPH receptor A4

    Omim ID

    602188

    Gene Ontology

    Hyperlink

    Gene Summary

    This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. [provided by RefSeq

    Other Designations

    OTTHUMP00000164185|TYRO1 protein tyrosine kinase|ephrin receptor EphA4|ephrin type-A receptor 4|receptor protein-tyrosine kinase HEK8|tyrosine-protein kinase receptor SEK

  • Interactome
  • Pathway
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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