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ROS1 (Human) Recombinant ProteinBioActive

  • Catalog # : P5637
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  • Specification
  • Product Description:
  • Human ROS1 (NP_002935.2, 1883 a.a. - 2347 a.a.) partial recombinant protein with GST tag expressed in baculovirus infected Sf21 cells.
  • Host:
  • Insect
  • Theoretical MW (kDa):
  • 79
  • Form:
  • Liquid
  • Preparation Method:
  • Baculovirus infected insect cell (Sf21) expression system
  • Purification:
  • Glutathione sepharose chromatography
  • Purity:
  • 54 % by SDS-PAGE/CBB staining
  • Activity:
  • The activity was measured by off-chip mobility shift assay. The enzyme was incubated with fluorescence-labeled substrate and Mg(or Mn)/ATP. The phosphorylated and unphosphorylated substrates were separated and detected by LabChip 3000. Substrate: IRS1. ATP: 100 uM.
  • Quality Control Testing:
  • Loading 1 ug protein in SDS-PAGE

    QC Testing of P5637
  • Storage Buffer:
  • In 50 mM Tris-HCl, 150 mM NaCl, pH 7.5 (0.05% Brij35, 1 mM DTT, 10% glycerol)
  • Storage Instruction:
  • Store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • Result of activity analysis

  • Applications
  • Functional Study
  • SDS-PAGE
  • Application Image
  • Functional Study
  • SDS-PAGE
  • Gene Information
  • Entrez GeneID:
  • 6098
  • Gene Name:
  • ROS1
  • Gene Alias:
  • MCF3,ROS,c-ros-1
  • Gene Description:
  • c-ros oncogene 1 , receptor tyrosine kinase
  • Gene Summary:
  • This proto-oncogene, highly-expressed in a variety of tumor cell lines, belongs to the sevenless subfamily of tyrosine kinase insulin receptor genes. The protein encoded by this gene is a type I integral membrane protein with tyrosine kinase activity. The protein may function as a growth or differentiation factor receptor. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000017814,OTTHUMP00000040389,proto-oncogene c-ros-1 protein,proto-oncogene tyrosine-protein kinase ROS,transmembrane tyrosine-specific protein kinase,v-ros UR2 sarcoma virus oncogene homolog 1,v-ros avian UR2 sarcoma virus oncogene homolog 1
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