TNFRSF10B (Human) Recombinant Protein with Fc
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Specification
Product Description
Human TNFRSF10B (1 a.a. - 182 a.a.) from HEK 293 cells with human IgG1 recombinant protein.
Host
Human
Theoretical MW (kDa)
45
Form
Lyophilized
Purification
Protein A purification
Purity
> 95% by SDS-PAGE
Endotoxin Level
< 0.1 EU/ug purified protein as determined by LAL test
Quality Control Testing
12% SDS-PAGE SDS-PAGE Stained with Coomassie Blue
Lane 1 to 4: TNFRSF10B (Human) Recombinant Protein with Fc (2000 ng, 1000 ng, 500 ng, 200 ng per lane).
Storage Buffer
Lyophilized from PBS
Storage Instruction
Store at -20°C on dry atmosphere for at least 6 months.
After reconstitution with 50 uL sterile deionized water, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing. -
Applications
SDS-PAGE
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Gene Info — TNFRSF10B
Entrez GeneID
8795Gene Name
TNFRSF10B
Gene Alias
CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9
Gene Description
tumor necrosis factor receptor superfamily, member 10b
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq
Other Designations
Fas-like protein|OTTHUMP00000123492|TNF-related apoptosis-inducing ligand receptor 2|TRAIL receptor 2|apoptosis inducing protein TRICK2A/2B|apoptosis inducing receptor TRAIL-R2|cytotoxic TRAIL receptor-2|death domain containing receptor for TRAIL/Apo-2L|d
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Disease
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