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Ubiquitin+1 (Human) Recombinant Protein

  • Catalog # : P5019
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  • Specification
  • Product Description:
  • Human Ubiquitin+1 (P62988, 1 a.a. - 96 a.a.) full-length recombinant protein with GST tag expressed in Escherichia coli.
  • Calibration Range:
  • 1 mg/mL
  • Host:
  • Escherichia coli
  • Theoretical MW (kDa):
  • 37
  • Form:
  • Liquid
  • Preparation Method:
  • Escherichia coli expression system
  • Purification:
  • GSH Sepharose
  • Purity:
  • > 95% by SDS-PAGE
  • Quality Control Testing:
  • 1 ug/lane in 12% SDS-PAGE Stained with Coomassie Blue

    QC Testing of P5019
  • Storage Buffer:
  • In 20 mM HEPES, pH 7.0 (10% glycerol)
  • Storage Instruction:
  • Store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • SDS-PAGE
  • Application Image
  • SDS-PAGE
  • Gene Information
  • Entrez GeneID:
  • 7314
  • Gene Name:
  • UBB
  • Gene Alias:
  • FLJ25987,MGC8385
  • Gene Description:
  • ubiquitin B
  • Gene Summary:
  • This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin is required for ATP-dependent, nonlysosomal intracellular protein degradation of abnormal proteins and normal proteins with a rapid turnover. Ubiquitin is covalently bound to proteins to be degraded, and presumably labels these proteins for degradation. Ubiquitin also binds to histone H2A in actively transcribed regions but does not cause histone H2A degradation, suggesting that ubiquitin is also involved in regulation of gene expression. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. Aberrant form of this protein has been noticed in patients with Alzheimer's and Down syndrome. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000064960,OTTHUMP00000064961,polyubiquitin B
  • Gene Pathway
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