CP (Human) Native Protein
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Specification
Product Description
Human CP native protein from normal human plasma.
Sequence
MKILILGIFLFLCSTPAWAKEKHYYIGIIETTWDYASDHGEKKLISVDTEHSNIYLQNGPDRIGRLYKKALYLQYTDETFRTTIEKPVWLGFLGPIIKAETGDKVYVHLKNLASRPYTFHSHGITYYKEHEGAIYPDNTTDFQRADDKVYPGEQYTYMLLATEEQSPGEGDGNCVTRIYHSHIDAPKDIASGLIGPLIICKKDSLDKEKEKHIDREFVVMFSVVDENFSWYLEDNIKTYCSEPEKVDKDNEDFQESNRMYSVNGYTFGSLPGLSMCAEDRVKWYLFGMGNEVDVHAAFFHGQALTNKNYRIDTINLFPATLFDAYMVAQNPGEWMLSCQNLNHLKAGLQAFFQVQECNKSSSKDNIRGKHVRHYYIAAEEIIWNYAPSGIDIFTKENLTAPGSDSAVFFEQGTTRIGGSYKKLVYREYTDASFTNRKERGPEEEHLGILGPVIWAEVGDTIRVTFHNKGAYPLSIEPIGVRFNKNNEGTYYSPNYNPQSRSVPPSASHVAPTETFTYEWTVPKEVGPTNADPVCLAKMYYSAVDPTKDIFTGLIGPMKICKKGSLHANGRQKDVDKEFYLFPTVFDENESLLLEDNIRMFTTAPDQVDKEDEDFQESNKMHSMNGFMYGNQPGLTMCKGDSVVWYLFSAGNEADVHGIYFSGNTYLWRGERRDTANLFPQTSLTLHMWPDTEGTFNVECLTTDHYTGGMKQKYTVNQCRRQSEDSTFYLGERTYYIAAVEVEWDYSPQREWEKELHHLQEQNVSNAFLDKGEFYIGSKYKKVVYRQYTDSTFRVPVERKAEEEHLGILGPQLHADVGDKVKIIFKNMATRPYSIHAHGVQTESSTVTPTLPGETLTYVWKIPERSGAGTEDSACIPWAYYSTVDQVKDLYSGLIGPLIVCRRPYLKVFNPRRKLEFALLFLVFDENESWYLDDNIKTYSDHPEKVNKDDEEFIESNKMHAINGRMFGNLQGLTMHVGDEVNWYLMGMGNEIDLHTVHFHGHSFQYKHRGVYSSDVFDIFPGTYQTLEMFPRTPGIWLLHCHVTDHIHAGMETTYTVLQNEDTKSG
Host
Human
Theoretical MW (kDa)
132
Form
Lyophilized
Preparation Method
Native protein purified from normal human plasma.
Purity
> 90% by SDS-PAGE
Storage Buffer
In 20mM Tris, pH 8.0 (5mM DTT).
Storage Instruction
Store at -80°C on dry atmosphere.
Reconstitute 1 mg of the protein with 1 mL of reagent grade water to generate a 1 mg/mL solution. Allow the protein solution to sit for 10 minutes with gentle agitaton prior to use. After reconstitution with reagent grade water, store at -60°C or lower.
Aliquot to avoid repeated freezing and thawing. -
Applications
SDS-PAGE
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Gene Info — CP
Entrez GeneID
1356Protein Accession#
P00450Gene Name
CP
Gene Alias
CP-2
Gene Description
ceruloplasmin (ferroxidase)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a metalloprotein that binds most of the copper in plasma and is involved in the peroxidation of Fe(II)transferrin to Fe(III) transferrin. Mutations in this gene cause aceruloplasminemia, which results in iron accumulation and tissue damage, and is associated with diabetes and neurologic abnormalities. [provided by RefSeq
Other Designations
ceruloplasmin|ferroxidase
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Interactome
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Pathway
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Disease
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Publication Reference
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Methods for predicting rheumatoid arthritis treatment response.
Olivier Vittecoq, Thierry Lequerre, Pascal Cosette, Olivier Boyer, Xavier Le Loet, Julie Hardouin, Antoine Obry.
United States Patent Application Publication 2016 May; [Epub].
Application：ELISA, Human, Serum.
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Methods for predicting rheumatoid arthritis treatment response.
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