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ADAMTS5 (d625-930) (Human) Recombinant ProteinBioActive

  • Catalog # : P4931
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  • Specification
  • Product Description:
  • Human ADAMTS5 amino acids 625-930 deleted recombinant protein with His tag expressed in insect cells.
  • Host:
  • Insect
  • Theoretical MW (kDa):
  • 40.8
  • Form:
  • Liquid
  • Preparation Method:
  • Insect cell expression system
  • Concentration:
  • 0.1 mg/mL
  • Purity:
  • >= 50% by SDS-PAGE
  • Activity:
  • >= 5 mU/mg
  • Quality Control Testing:
  • 15% SDS-PAGE Stained with Coomassie Blue

    QC Testing of P4931
  • Storage Buffer:
  • In 50 mM Tris-HCl, 150 mM NaCl, 5 mM CaCl2, pH 7.5 (50 mM imidazol, 0.05% Brij-35 detergent)
  • Storage Instruction:
  • Store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Functional Study
  • SDS-PAGE
  • Application Image
  • Functional Study
  • SDS-PAGE
  • Gene Information
  • Gene Name:
  • ADAMTS5
  • Gene Alias:
  • ADAMTS11,ADMP-2,FLJ36738
  • Gene Description:
  • ADAM metallopeptidase with thrombospondin type 1 motif, 5
  • Gene Summary:
  • This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains two C-terminal TS motifs and functions as aggrecanase to cleave aggrecan, a major proteoglycan of cartilage. [provided by RefSeq
  • Other Designations:
  • a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2),aggrecanase-2
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