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Last updated: 2016/12/4

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MMP8 (Human) Native ProteinBioActive

  • Catalog # : P4920
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  • Specification
  • Product Description:
  • Human MMP8 (447 amino acids ) full-length native protein from human blood.
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 75
  • Form:
  • Liquid
  • Preparation Method:
  • Native protein purified from human blood
  • Purification:
  • Affinity Chromatography/Gelfiltration
  • Concentration:
  • 0.2 mg/mL
  • Purity:
  • > 95% by SDS-PAGE
  • Activity:
  • > 20 mU/mg
  • Quality Control Testing:
  • 15% SDS-PAGE Stained with Coomassie Blue

    QC Testing of P4920
  • Storage Buffer:
  • In 50 mM Tris-HCl, 200 mM NaCl, 5 mM CaCl2, pH 7.0 (0.05% sodium azid, 0.05% Brij-35 detergent)
  • Storage Instruction:
  • Store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Functional Study
  • SDS-PAGE
  • Application Image
  • Functional Study
  • SDS-PAGE
  • Gene Information
  • Entrez GeneID:
  • 4317
  • Gene Name:
  • MMP8
  • Gene Alias:
  • CLG1,HNC,PMNL-CL
  • Gene Description:
  • matrix metallopeptidase 8 (neutrophil collagenase)
  • Gene Summary:
  • Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is stored in secondary granules within neutrophils and is activated by autolytic cleavage. Its function is degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq
  • Other Designations:
  • PMNL collagenase,matrix metalloproteinase 8,matrix metalloproteinase 8 (neutrophil collagenase),neutrophil collagenase
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