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MMP1 (Human) Native ProteinBioActive

  • Catalog # : P4919
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  • Specification
  • Product Description:
  • Human MMP1 native protein from human fibroblasts.
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 52-56
  • Form:
  • Liquid
  • Preparation Method:
  • Native protein purified from human fibroblasts
  • Purification:
  • Affinity Chromatography/Ion Exchange Chromatography/Gelfiltration
  • Concentration:
  • 0.2 mg/mL
  • Purity:
  • > 90% by SDS-PAGE
  • Activity:
  • >= 100 mU/mg (upon trypsin activation)
  • Quality Control Testing:
  • 15% SDS-PAGE Stained with Coomassie Blue

    QC Testing of P4919
  • Storage Buffer:
  • In 50 mM Tris-HCl, 300 mM NaCl, 5 mM CaCl2, 1 uM ZnCl2, pH 7.0 (0.05% sodium azid, 0.05% Brij-35 detergent)
  • Storage Instruction:
  • Store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Functional Study
  • SDS-PAGE
  • Application Image
  • Functional Study
  • SDS-PAGE
  • Gene Information
  • Entrez GeneID:
  • 4312
  • Gene Name:
  • MMP1
  • Gene Alias:
  • CLG,CLGN
  • Gene Description:
  • matrix metallopeptidase 1 (interstitial collagenase)
  • Gene Summary:
  • Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants.[provided by RefSeq
  • Other Designations:
  • fibroblast collagenase,interstitial collagenase,matrix metalloprotease 1,matrix metalloproteinase 1,matrix metalloproteinase 1 (interstitial collagenase)
  • Interactome
  • Interactome
  • Related Disease
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