KDR (Human) Recombinant Protein
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specification
Product Description
Human KDR (NM_002253, 807 a.a. - 1356 a.a.) partial Recombinant protein with GST tag expressed in Sf9 cells.
Host
insect
Theoretical MW (kDa)
87.095
Form
Liquid
Preparation Method
Insect cell (Sf9) expression system
Purification
GST-Affinity Chromatography
Concentration
0.072 ug/uL
Activity
218 pmol/ug x min
Quality Control Testing
2 ug/lane SDS-PAGE Stained with Coomassie Blue
Storage Buffer
In 50 mM Hepes, 100 mM NaCl, pH 7.5 (5 mM DTT, 4 mM reduced glutathione, 20% glycerol)
Storage Instruction
Store at -80°C.
Aliquot to avoid repeated freezing and thawingNote
Result of activity analysis
-
Applications
Functional Study
SDS-PAGE
-
Gene Info — KDR
Entrez GeneID
3791Protein Accession#
NM_002253Gene Name
KDR
Gene Alias
CD309, FLK1, VEGFR, VEGFR2
Gene Description
kinase insert domain receptor (a type III receptor tyrosine kinase)
Gene Ontology
HyperlinkGene Summary
Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq
Other Designations
soluble VEGFR2|vascular endothelial growth factor receptor 2
-
Interactome
-
Pathway
-
Disease
- Adenocarcinoma
- Alzheimer disease
- Angina Pectoris
- Anoxia
- Asthma
- Brain Neoplasms
- Breast cancer
- Breast Neoplasms
- Carcinoma
+ View More Disease
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com