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NTRK1 (Human) Recombinant ProteinBioActive

  • Catalog # : P4785
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  • Specification
  • Product Description:
  • Human NTRK1 (NM_002529.2, 443 a.a. - 796 a.a.) partial recombinanat protein with GST-His tag expressed in Sf9 cells.
  • Host:
  • Insect
  • Theoretical MW (kDa):
  • 69.726
  • Form:
  • Liquid
  • Preparation Method:
  • Insect cell (Sf9) expression system
  • Purification:
  • GST-Affinity Chromatography
  • Activity:
  • 100 pmol/ug x min
  • Quality Control Testing:
  • 2 ug/lane SDS-PAGE Stained with Coomassie Blue

    QC Testing of P4785
  • Storage Buffer:
  • In 50 mM HEPES, 100 mM NaCl, pH 7.5 (5 mM DTT, 15 mM reduced glutathione, 20% glycerol)
  • Storage Instruction:
  • Store at -80°C.
    Aliquot to avoid repeated freezing and thawing
  • Note:
  • Result of activity analysis

  • Applications
  • Functional Study
  • SDS-PAGE
  • Application Image
  • Functional Study
  • SDS-PAGE
  • Gene Information
  • Entrez GeneID:
  • 4914
  • Gene Name:
  • NTRK1
  • Gene Alias:
  • DKFZp781I14186,MTC,TRK,TRK1,TRKA,p140-TrkA
  • Gene Description:
  • neurotrophic tyrosine kinase, receptor, type 1
  • Gene Summary:
  • This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000038736,Oncogene TRK,high affinity nerve growth factor receptor,tyrosine kinase receptor A
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