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TGFBR1 (Human) Recombinant ProteinBioActive

  • Catalog # : P4783
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  • Specification
  • Product Description:
  • Human TGFBR1 (NM_004612, 200 a.a. - 503 a.a.) partial recombinant protein with GST-His tag expressed in Sf9 cells.
  • Host:
  • Insect
  • Theoretical MW (kDa):
  • 64.168
  • Form:
  • Liquid
  • Preparation Method:
  • Insect cell (Sf9) expression system
  • Purification:
  • GST affinity chromatography
  • Concentration:
  • 0.193 ug/uL
  • Activity:
  • 501 pmol/ug x min
  • Quality Control Testing:
  • 2 ug/lane SDS-PAGE Stained with Coomassie Blue

    QC Testing of P4783
  • Storage Buffer:
  • In 50 mM Hepes, 100 mM NaCl, pH 7.5. (5 mM DTT, 15 mM reduced glutathione, 20% glycerol)
  • Storage Instruction:
  • Store at -80°C.
    Aliquot to avoid repeated freezing and thawing
  • Note:
  • Result of activity analysis

  • Applications
  • Functional Study
  • SDS-PAGE
  • Application Image
  • Functional Study
  • SDS-PAGE
  • Gene Information
  • Entrez GeneID:
  • 7046
  • Gene Name:
  • TGFBR1
  • Gene Alias:
  • AAT5,ACVRLK4,ALK-5,ALK5,LDS1A,LDS2A,SKR4,TGFR-1
  • Gene Description:
  • transforming growth factor, beta receptor 1
  • Gene Summary:
  • The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000021783,activin A receptor type II-like kinase, 53kD,activin A receptor type II-like kinase, 53kDa,activin receptor-like kinase 5,serine/threonine-protein kinase receptor R4,transforming growth factor beta receptor I,transforming growth factor,
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