SGK1 (Human) Recombinant Protein
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Specification
Product Description
Human SGK1 (NM_005627.2, 1 a.a. - 431 a.a.) full-length recombinant protein with GST tag expressed in Sf9 cells.
Host
insect
Theoretical MW (kDa)
74.95
Form
Liquid
Preparation Method
Insect cell (Sf9) expression system
Purification
GST affinity chromatography
Concentration
0.126 ug/uL
Activity
54 pmol/ug x min
Quality Control Testing
2 ug/lane SDS-PAGE Stained with Coomassie Blue
Storage Buffer
In 50 mM Hepes, 100 mM NaCl, pH 7.5. (5 mM DTT, 15 mM reduced glutathione, 20% glycerol)
Storage Instruction
Store at -80°C.
Aliquot to avoid repeated freezing and thawingNote
Result of activity analysis
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Applications
Functional Study
SDS-PAGE
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Gene Info — SGK1
Entrez GeneID
6446Protein Accession#
NM_005627.2Gene Name
SGK1
Gene Alias
SGK
Gene Description
serum/glucocorticoid regulated kinase 1
Omim ID
602958Gene Ontology
HyperlinkGene Summary
This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000017247|serine/threonine protein kinase SGK
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