MAPKAPK5 (Human) Recombinant Protein
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Result of activity analysis
Result of activity analysis
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Specification
Product Description
Human MAPKAPK5 (NM_003668.2, 1 a.a. - 471 a.a.) full-length recombinant protein expressed in Escherichia coli.
Host
Escherichia coli
Theoretical MW (kDa)
54.161
Form
Liquid
Preparation Method
Escherichia coli expression system
Purification
Immobilized metal affinity chromatography
Concentration
0.772 ug/uL
Activity
11 pmol/ug x min
Quality Control Testing
2 ug/lane SDS-PAGE Stained with Coomassie Blue
Storage Buffer
In 50 mM Hepes, 100 mM NaCl, pH 7.5. (5 mM DTT, 20% glycerol)
Storage Instruction
Store at -80°C.
Aliquot to avoid repeated freezing and thawingNote
Result of activity analysis
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Applications
Functional Study
SDS-PAGE
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Gene Info — MAPKAPK5
Entrez GeneID
8550Protein Accession#
NM_003668.2Gene Name
MAPKAPK5
Gene Alias
PRAK
Gene Description
mitogen-activated protein kinase-activated protein kinase 5
Omim ID
606723Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. In vitro, this kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq
Other Designations
p38-regulated/activated protein kinase
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Interactome
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Pathway
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