JAK2 (Human) Recombinant Protein
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Specification
Product Description
Human JAK2 (NM_004972.2, 717 a.a. - 1132 a.a.) partial recombinant protein with GST-His tag expressed in Sf9 cells.
Host
insect
Theoretical MW (kDa)
78.512
Form
Liquid
Preparation Method
Insect cell (Sf9) expression system
Purification
GST affinity chromatography
Concentration
0.091 ug/uL
Activity
24 pmol/ug x min
Quality Control Testing
2 ug/lane SDS-PAGE Stained with Coomassie Blue
Storage Buffer
In 50 mM Hepes, 100 mM NaCl, pH 7.5. (5 mM DTT, 4 mM reduced glutathione, 20% glycerol)
Storage Instruction
Store at -80°C.
Aliquot to avoid repeated freezing and thawingNote
Result of activity analysis
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Applications
Functional Study
SDS-PAGE
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Gene Info — JAK2
Entrez GeneID
3717Protein Accession#
NM_004972.2Gene Name
JAK2
Gene Alias
JTK10
Gene Description
Janus kinase 2 (a protein tyrosine kinase)
Gene Ontology
HyperlinkGene Summary
This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis. [provided by RefSeq
Other Designations
Janus kinase 2|OTTHUMP00000021024|OTTHUMP00000043260|tyrosine-protein kinase JAK2
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Interactome
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