EIF2AK1 (Human) Recombinant Protein
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Specification
Product Description
Human EIF2AK1 (NM_014413.2, 1 a.a. - 630 a.a.) full-length recombinant protein, Δ244, with GST-His6 tag at N-terminal with a Thrombin cleavage site expressed in Sf9 cells.
Host
insect
Theoretical MW (kDa)
100.546
Form
Liquid
Preparation Method
Insect cell (Sf9) expression system
Purification
GST affinity chromatography
Concentration
0.030 ug/uL
Activity
3 pmol/ug x min
Quality Control Testing
2 ug/lane SDS-PAGE Stained with Coomassie Blue
Storage Buffer
In 50 mM Hepes, 100 mM NaCl, pH 7.5. (5 mM DTT, 4 mM reduced glutathione, 20% glycerol)
Storage Instruction
Store at -80°C.
Aliquot to avoid repeated freezing and thawingNote
Result of activity analysis
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Applications
Functional Study
SDS-PAGE
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Gene Info — EIF2AK1
Entrez GeneID
27102Protein Accession#
NM_014413.2Gene Name
EIF2AK1
Gene Alias
HCR, HRI, KIAA1369
Gene Description
eukaryotic translation initiation factor 2-alpha kinase 1
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene acts at the level of translation initiation to downregulate protein synthesis in response to stress. The encoded protein is a kinase that can be inactivated by hemin. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
heme regulated initiation factor 2 alpha kinase|heme sensitive initiation factor 2a kinase|heme-regulated inhibitor|heme-regulated initiation factor 2-alpha kinase|heme-regulated repressor
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Interactome
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Disease
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