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Last updated: 2017/9/24

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IL16 (Human) Recombinant ProteinBioActive

  • Catalog # : P4563
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  • Specification
  • Product Description:
  • Human IL16 (AAC12732) recombinant protein expressed in Escherichia coli.
  • Sequence:
  • MPDLNSSTDSAASASAASDVSVESTAEATVCTVTLEKMSAGLGFSLEGGKGSLHGDKPLTINRIFKGAASEQSETVQPGDEILQLGGTAMQGLTRFEAWNIIKALPDGPVTIVIRRKSLQSKETTAAGDS
  • Host:
  • Escherichia coli
  • Theoretical MW (kDa):
  • 13.5
  • Form:
  • Lyophilized
  • Preparation Method:
  • Escherichia coli expression system
  • Endotoxin Level:
  • < 0.1 EU/ug
  • Activity:
  • The activity is determined by the ability to chemoattract human T lymphocytes and is detectable starting at 5 ng/mL.
  • Quality Control Testing:
  • 1 ug/lane in 4-20% Tris-Glycine gel Stained with Coomassie Blue

    QC Testing of P4563
    Lane 1: non-reducing conditions
    Lane 2: reducing conditions
  • Storage Buffer:
  • Lyophilized 10 mM Na2PO4, pH 7.5.
  • Storage Instruction:
  • Store at -20°C on dry atmosphere.
    After reconstitution with sterilized water, store at -20°C or lower.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • Result of activity analysis
  • Human T cells were allowed to migrate to human IL16 at (0, 5, 20, 100 and 500 ng/mL). After 4 hours, cells that migrated were counted using a luminescent substrate and displayed on the bar graph above.


  • Applications
  • Functional Study
  • SDS-PAGE
  • Application Image
  • Functional Study
  • SDS-PAGE
  • Gene Information
  • Entrez GeneID:
  • 3603
  • Gene Name:
  • IL16
  • Gene Alias:
  • FLJ16806,FLJ42735,FLJ44234,HsT19289,IL-16,LCF,prIL-16
  • Gene Description:
  • interleukin 16 (lymphocyte chemoattractant factor)
  • Gene Summary:
  • The protein encoded by this gene is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. The product of this gene undergoes proteolytic processing, which is found to yield two functional proteins. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000190849,OTTHUMP00000190850,interleukin 16,lymphocyte chemoattractant factor
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