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IL2 (Human) Recombinant ProteinBioActive

  • Catalog # : P4560
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  • Specification
  • Product Description:
  • Human IL2 (P60568) recombinant protein expressed in Escherichia coli.
  • Sequence:
  • MAPTSSSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPKKATELKHLQCLEEELKPLEEVLNLAQSKNFHLRPRDLISNINVIVLELKGSETTFMCEYADETATIVEFLNRWITFSQSIISTLT
  • Host:
  • Escherichia coli
  • Theoretical MW (kDa):
  • 15.5
  • Form:
  • Lyophilized
  • Preparation Method:
  • Escherichia coli expression system
  • Endotoxin Level:
  • < 0.1 EU/ug
  • Activity:
  • The activity is determined by the dose dependent induced proliferation of CTLL-2 cells. The expected ED50 for this effect is 2.1-3.1 ng/mL.
  • Quality Control Testing:
  • 1 ug/lane in 4-20% Tris-Glycine gel Stained with Coomassie Blue

    QC Testing of P4560
    Lane 1: non-reducing conditions
    Lane 2: reducing conditions
  • Storage Buffer:
  • Lyophilized with sodium citrate, pH 3.0.
  • Storage Instruction:
  • Store at -20°C on dry atmosphere.
    After reconstitution with 10 mM HCl, store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Functional Study
  • SDS-PAGE
  • Application Image
  • Functional Study
  • SDS-PAGE
  • Gene Information
  • Entrez GeneID:
  • 3558
  • Gene Name:
  • IL2
  • Gene Alias:
  • IL-2,TCGF,lymphokine
  • Gene Description:
  • interleukin 2
  • Gene Summary:
  • The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. [provided by RefSeq
  • Other Designations:
  • T cell growth factor,aldesleukin,interleukin-2,involved in regulation of T-cell clonal expansion
  • Related Disease
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