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MMP11 (Human) Recombinant Protein

  • Catalog # : P4554
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  • Specification
  • Product Description:
  • Human MMP11 (NP_005931.1, 33 a.a. - 488 a.a.) partial recombinant protein with His-GST tag expressed in Escherichia coli.
  • Host:
  • Escherichia coli
  • Theoretical MW (kDa):
  • 79.817
  • Form:
  • Liquid
  • Preparation Method:
  • Escherichia coli expression system
  • Purity:
  • > 80% by SDS-PAGE
  • Quality Control Testing:
  • 10% SDS-PAGE Stained with Coomassie Blue

    QC Testing of P4554
  • Storage Buffer:
  • In 20mM Sodium Phosphate, 0.5M NaCl, 0.15M imidazole, pH 7.4.
  • Storage Instruction:
  • Store at -80°C.
    Aliquot to avoid repeated freezing and thawing
  • Applications
  • SDS-PAGE
  • Application Image
  • SDS-PAGE
  • Gene Information
  • Entrez GeneID:
  • 4320
  • Gene Name:
  • MMP11
  • Gene Alias:
  • SL-3,ST3,STMY3
  • Gene Description:
  • matrix metallopeptidase 11 (stromelysin 3)
  • Gene Summary:
  • Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix. [provided by RefSeq
  • Other Designations:
  • matrix metalloproteinase 11,matrix metalloproteinase 11 (stromelysin 3),stromelysin 3,stromelysin III
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