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Last updated: 2017/12/10

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GPX4 (U73C) (Human) Recombinant Protein

  • Catalog # : P4548
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  • Specification
  • Product Description:
  • Human GPX4 (P36969, 25 a.a. - 197 a.a.) U73C mutant partial recombinant protein expressed in Escherichia coli.
  • Host:
  • Escherichia coli
  • Theoretical MW (kDa):
  • 19
  • Form:
  • Lyophilized
  • Preparation Method:
  • Escherichia coli expression system
  • Purity:
  • > 95% by SDS-PAGE
  • Quality Control Testing:
  • 1ug/lane 12% SDS-PAGE Stained with Coomassie Blue

    QC Testing of P4548
  • Storage Buffer:
  • Lyophilized from 20 mM Hepes, pH 7.4
  • Storage Instruction:
  • Store at -20°C.
    After reconstitution, store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • SDS-PAGE
  • Application Image
  • SDS-PAGE
  • Gene Information
  • Entrez GeneID:
  • 2879
  • Gene Name:
  • GPX4
  • Gene Alias:
  • MCSP,PHGPx,snGPx,snPHGPx
  • Gene Description:
  • glutathione peroxidase 4 (phospholipid hydroperoxidase)
  • Gene Summary:
  • Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme and the UGA codon is translated into a selenocysteine. Through alternative splicing and transcription initiation, rat produces proteins that localize to the nucleus, mitochondrion, and cytoplasm. In humans, experimental evidence for alternative splicing exists; alternative transcription initiation and the cleavage sites of the mitochondrial and nuclear transit peptides need to be experimentally verified. [provided by RefSeq
  • Other Designations:
  • glutathione peroxidase 4,phospholipid hydroperoxidase,phospholipid hydroperoxide glutathione peroxidase, mitochondrial,sperm nucleus glutathione peroxidase
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