GPX2 (Human) Recombinant Protein
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Specification
Product Description
Human GPX2 (NP_002074, 1 a.a. - 190 a.a.) full-length recombinant protein with His tag expressed in Escherichia coli.
Sequence
MGSSHHHHHHSSGLVPRGSHMAFIAKSFYDLSAISLDGEKVDFNTFRGRAVLIENVASLCGTTTRDFTQLNELQCRFPRRLVVLGFPCNQFGHQENCQNEEILNSLKYVRPGGGYQPTFTLVQKCEVNGQNEHPVFAYLKDKLPYPYDDPFSLMTDPKLIIWSPVRRSDVAWNFEKFLIGPEGEPFRRYSRTFPTINIEPDIKRLLKVAI
Host
Escherichia coli
Theoretical MW (kDa)
24.1
Form
Liquid
Preparation Method
Escherichia coli expression system
Concentration
0.25 mg/mL
Purity
> 95% by SDS - PAGE
Quality Control Testing
15% SDS-PAGE Stained with Coomassie Blue
Storage Buffer
In 20 mM Tris-HCl buffer, 0.15 M NaCl, pH7.5 (40% glycerol, 1 mM DTT).
Storage Instruction
Store at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Functional Study
SDS-PAGE
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Gene Info — GPX2
Entrez GeneID
2877Protein Accession#
NP_002074Gene Name
GPX2
Gene Alias
GI-GPx, GPRP, GSHPX-GI, GSHPx-2
Gene Description
glutathione peroxidase 2 (gastrointestinal)
Omim ID
138319Gene Ontology
HyperlinkGene Summary
This gene is a member of the glutathione peroxidase family and encodes a selenium-dependent glutathione peroxidase that is one of two isoenzymes responsible for the majority of the glutathione-dependent hydrogen peroxide-reducing activity in the epithelium of the gastrointestinal tract. Studies in knockout mice indicate that mRNA expression levels respond to luminal microflora, suggesting a role of the ileal glutathione peroxidases in preventing inflammation in the GI tract. [provided by RefSeq
Other Designations
gastrointestinal glutathione peroxidase 2|glutathione peroxidase 2|glutathione peroxidase-related protein 2
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Interactome
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