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CCL7 (Human) Recombinant ProteinBioActive

  • Catalog # : P4424
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  • Specification
  • Product Description:
  • Human CCL7 (Q7Z7Q8) recombinant protein expressed in Escherichia coli.
  • Sequence:
  • QPVGINTSTTCCYRFINKKIPKQRLESYRRTTSSHCPREAVIFKTKLDKEICADPTQKWVQDFMKHLDKKTQTPKL
  • Host:
  • Escherichia coli
  • Theoretical MW (kDa):
  • 9
  • Form:
  • Lyophilized
  • Preparation Method:
  • Escherichia coli expression system
  • Endotoxin Level:
  • < 0.1 EU/ug
  • Activity:
  • The activity is determined by the ability of MCP-3 to chemoattract THP-1 cells and is detectable starting at 10 ng/mL.
  • Quality Control Testing:
  • 1 ug/lane in 4-20% Tris-Glycine gel Stained with Coomassie Blue

    QC Testing of P4424
    Lane 1: non-reducing conditions
    Lane 2: reducing conditions
  • Storage Buffer:
  • No additive
  • Storage Instruction:
  • Store at -20°C on dry atmosphere.
    After reconstitution with sterilized water, store at -20°C or lower.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • Result of activity analysis
  • Human THP-1 cells were allowed to migrate to human CCL7 at (0, 0.1, 1, 10, 100 and 1000 ng/mL). After 45 minutes, cells that migrated were counted using a luminescent substrate and displayed on the bar graph above.


  • Applications
  • Functional Study
  • SDS-PAGE
  • Application Image
  • Functional Study
  • SDS-PAGE
  • Gene Information
  • Entrez GeneID:
  • 6354
  • Gene Name:
  • CCL7
  • Gene Alias:
  • FIC,MARC,MCP-3,MCP3,MGC138463,MGC138465,NC28,SCYA6,SCYA7
  • Gene Description:
  • chemokine (C-C motif) ligand 7
  • Gene Summary:
  • This gene encodes monocyte chemotactic protein 3, a secreted chemokine which attracts macrophages during inflammation and metastasis. It is a member of the C-C subfamily of chemokines which are characterized by having two adjacent cysteine residues. The protein is an in vivo substrate of matrix metalloproteinase 2, an enzyme which degrades components of the extracellular matrix. This gene is part of a cluster of C-C chemokine family members on chromosome 17q. [provided by RefSeq
  • Other Designations:
  • monocyte chemoattractant protein 3,monocyte chemotactic protein 3,small inducible cytokine A7 (monocyte chemotactic protein 3)
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