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IL19 (Human) Recombinant ProteinBioActive

  • Catalog # : P4410
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  • Specification
  • Product Description:
  • Human IL19 (Q9UHD0) recombinant protein expressed in Escherichia coli.
  • Sequence:
  • mLRRCLISTDMHHIEESFQEIKRAIQAKDTFPNVTILSTLETLQIIKPLDVCCVTKNLLAFYVDRVFKDHQEPNPKILRKISSIANSFLYMQKTLRQCQEQRQCHCRQEATNATRVIHDNYDQLEVHAAAIKSLGELDVFLAWINKNHEVMSSA
  • Host:
  • Escherichia coli
  • Theoretical MW (kDa):
  • 17.9
  • Form:
  • Lyophilized
  • Preparation Method:
  • Escherichia coli expression system
  • Endotoxin Level:
  • < 0.1 EU/ug
  • Activity:
  • The activity is determined by the activation of STAT following receptor-ligand interaction.
  • Quality Control Testing:
  • 1 ug/lane in 4-20% Tris-Glycine gel Stained with Coomassie Blue

    QC Testing of P4410
    Non-reducing conditions
  • Storage Buffer:
  • Lyophilized from 10 mM sodium citrate, pH 5.0
  • Storage Instruction:
  • Store at -20°C on dry atmosphere.
    After reconstitution with sterilized water, store at -20°C or lower.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Functional Study
  • SDS-PAGE
  • Application Image
  • Functional Study
  • SDS-PAGE
  • Gene Information
  • Gene Name:
  • IL19
  • Gene Alias:
  • IL-10C,MDA1,NG.1,ZMDA1
  • Gene Description:
  • interleukin 19
  • Gene Summary:
  • The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described. [provided by RefSeq
  • Other Designations:
  • melanoma differentiation associated protein-like protein
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