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FGF2 (Human) Recombinant ProteinBioActive

  • Catalog # : P4386
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  • Specification
  • Product Description:
  • Human FGF2 (P09038) recombinant protein expressed in Escherichia coli.
  • Sequence:
  • Host:
  • Escherichia coli
  • Theoretical MW (kDa):
  • 16.5
  • Form:
  • Lyophilized
  • Preparation Method:
  • Escherichia coli expression system
  • Endotoxin Level:
  • < 0.1 EU/ug
  • Activity:
  • The activity is determined by the dose-dependent proliferation of mouse BALB/c 3T3 cells. The expected ED50 for this effect is 0.1-0.14 ng/mL.
  • Quality Control Testing:
  • 1 ug/lane in 4-20% Tris-Glycine gel Stained with Coomassie Blue

    QC Testing of P4386
    Lane 1: reducing conditions
    Lane 2: non-reducing conditions
  • Storage Buffer:
  • Lyophilized from 10 mM Na2PO4, pH 8.0
  • Storage Instruction:
  • Store at -20°C on dry atmosphere.
    After reconstitution with sterilized water, store at -20°C or lower.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Functional Study
  • Application Image
  • Functional Study
  • Gene Information
  • Entrez GeneID:
  • 2247
  • Gene Name:
  • FGF2
  • Gene Alias:
  • Gene Description:
  • fibroblast growth factor 2 (basic)
  • Gene Summary:
  • The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF. [provided by RefSeq
  • Other Designations:
  • basic fibroblast growth factor bFGF,fibroblast growth factor 2,heparin-binding growth factor 2,prostatropin
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