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TNFSF13B (Human) Recombinant ProteinBioActive

  • Catalog # : P4374
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  • Specification
  • Product Description:
  • Human TNFSF13B (Q9Y275) recombinant protein expressed in Escherichia coli.
  • Sequence:
  • Host:
  • Escherichia coli
  • Theoretical MW (kDa):
  • 17.2
  • Form:
  • Lyophilized
  • Preparation Method:
  • Escherichia coli expression system
  • Endotoxin Level:
  • < 0.1 EU/ug
  • Activity:
  • The activity is determined by a proliferation assay of RPMI-8226 cells in the presence of 0.2 uM DEX. The expected ED50 for this effect is 8.6-12.9 ng/mL.
  • Quality Control Testing:
  • 1 ug/lane in 4-20% Tris-Glycine gel Stained with Coomassie Blue

    QC Testing of P4374
    Lane 1: non-reducing conditions
    Lane 2: reducing conditions
  • Storage Buffer:
  • Lyophilized from 10 mM Na2PO4, pH 7.5
  • Storage Instruction:
  • Store at -20°C on dry atmosphere.
    After reconstitution with sterilized water, store at -20°C or lower.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • Result of activity analysis
  • RPMI-8226 cells were cultured with 0 to 500 ng/mL human TNFSF13B in the presence of 0.2 uM DEX. Cell proliferation was measured after 94 hours and the linear portion of the curve was us used to calculate the ED50.

  • Applications
  • Functional Study
  • Application Image
  • Functional Study
  • Gene Information
  • Gene Name:
  • TNFSF13B
  • Gene Alias:
  • Gene Description:
  • tumor necrosis factor (ligand) superfamily, member 13b
  • Gene Summary:
  • The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. This cytokine is expressed in B cell lineage cells, and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells. [provided by RefSeq
  • Other Designations:
  • ApoL related ligand TALL-1,B-cell activating factor,B-lymphocyte stimulator,OTTHUMP00000018691,TNF and ApoL-related leukocyte expressed ligand 1,TNF homolog that activates apoptosis,delta BAFF,dendritic cell-derived TNF-like molecule,tumor necrosis factor
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