UPK3A (Human) Recombinant Protein
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Specification
Product Description
Human UPK3A (BAA31460, 19 a.a. - 207 a.a.) partial recombinant protein with His tag expressed in Escherichia coli.
Sequence
MGSSHHHHHHSSGLVPRGSHMGSHMVNLQPQLASVTFATNNPTLTTVALEKPLCMFDSKEALTGTHEVYLYVLVDSAISRNASVQDSTNTPLGSTFLQTEGGRTGPYKAVAFDLIPCSDLPSLDAIGDVSKASQILNAYLVRVGANGTCLWDPNFQGLCNPPLSAATEYRFKYVLVNMSTGLVEDQTLWSDPIRTNQLTPYSTIDTWPGRRSGG
Host
Escherichia coli
Theoretical MW (kDa)
23.1
Form
Liquid
Preparation Method
Escherichia coli expression system
Concentration
0.25 mg/mL
Purity
> 90% by SDS-PAGE
Quality Control Testing
15% SDS-PAGE Stained with Coomassie Blue
Storage Buffer
In 20 mM Tris-HCl buffer, 150 mM NaCl, pH 8.0 (20% glycerol, 2 mM DTT).
Storage Instruction
Store at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
SDS-PAGE
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Gene Info — UPK3A
Entrez GeneID
7380Protein Accession#
BAA31460Gene Name
UPK3A
Gene Alias
MGC119178, UPIII, UPIIIA, UPK3
Gene Description
uroplakin 3A
Omim ID
611559Gene Ontology
HyperlinkGene Summary
Uroplakins (UPK) are integral membrane proteins that form 2-dimensional crystalline arrays termed urothelial plaques that cover more than 90% of the apical urothelial surface. The asymmetric unit membrane (AUM) forms the apical plaques of urothelium and is believed to strengthen the urothelial apical surface and prevent the cells from rupturing during bladder distention. The 4 major conserved integral membrane proteins of the AUM are UPK1A (MIM 611557), UPK1B (MIM 602380), UPK2 (MIM 611558), and UPK3A.[supplied by OMIM
Other Designations
OTTHUMP00000028951|uroplakin III
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