SUMF1 (Human) Recombinant Protein
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Specification
Product Description
Human SUMF1 (NP_877437, 91 a.a. - 374 a.a.) partial recombinant protein with His tag expressed in Escherichia coli.
Sequence
MGSSHHHHHHSSGLVPRGSHMVPIPAGVFTMGTDDPQIKQDGEAPARRVTIDAFYMDAYEVSNTEFEKFVNSTGYLTEAEKFGDSFVFEGmLSEQVKTNIQQAVAAAPWWLPVKGANWRHPEGPDSTILHRPDHPVLHVSWNDAVAYCTWAGKRLPTEAEWEYSCRGGLHNRLFPWGNKLQPKGQHYANIWQGEFPVTNTGEDGFQGTAPVDAFPPNGYGLYNIVGNAWEWTSDWWTVHHSVEETLNPKGPPSGKDRVKKGGSYMCHRSYCYRYRCAARSQNTPDSSASNLGFRCAADRLPTMD
Host
Escherichia coli
Theoretical MW (kDa)
34.1
Form
Liquid
Preparation Method
Escherichia coli expression system
Concentration
0.5 mg/mL
Purity
> 85% by SDS-PAGE
Quality Control Testing
15% SDS-PAGE Stained with Coomassie Blue
Storage Buffer
In 20 mM Tris-HCl buffer, pH 8.0 (20% glycerol, 2 M urea, 2 mM DTT).
Storage Instruction
Store at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
SDS-PAGE
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Gene Info — SUMF1
Entrez GeneID
285362Protein Accession#
NP_877437Gene Name
SUMF1
Gene Alias
AAPA3037, FGE, MGC131853, MGC150436
Gene Description
sulfatase modifying factor 1
Gene Ontology
HyperlinkGene Summary
This gene encodes an enzyme that catalyzes the hydrolysis of sulfate esters by oxidizing a cysteine residue in the substrate sulfatase to an active site 3-oxoalanine residue, which is also known as C-alpha-formylglycine. Mutations in this gene cause multiple sulfatase deficiency, a lysosomal storage disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq
Other Designations
C-alpha-formylglycine-generating enzyme|OTTHUMP00000115300
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Interactome
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Disease
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