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MAPKAPK3 (Human) Recombinant ProteinBioActive

  • Catalog # : P4238
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  • Specification
  • Product Description:
  • Human MAPKAPK3 (Q16644) full-length recombinant protein with GST expressed in Sf9 cells.
  • Host:
  • Insect
  • Theoretical MW (kDa):
  • 69
  • Form:
  • Liquid
  • Purity:
  • >= 90% by SDS-PAGE
  • Activity:
  • 636 nmol phosphate incorporated into MBP protein per minute per mg protein at 30°C for 15 minutes using a final concentration of 50 uM ATP (0.83 uCi/assay).
  • Quality Control Testing:
  • 1.5 ug/lane SDS-PAGE Stained with Coomassie Blue

    QC Testing of P4238
  • Storage Buffer:
  • In 50 mM Tris-HCl, 150 mM NaCl, pH 7.5 (0.25 mM Dithiothreitol, 0.1 mM EGTA, 0.1 mM EDTA, 25% glycerol, 0.1 mM PMSF)
  • Storage Instruction:
  • Store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • Result of activity analysis

  • Applications
  • Functional Study
  • Application Image
  • Functional Study
  • Gene Information
  • Entrez GeneID:
  • 7867
  • Gene Name:
  • Gene Alias:
  • Gene Description:
  • mitogen-activated protein kinase-activated protein kinase 3
  • Gene Summary:
  • This gene encodes a member of the Ser/Thr protein kinase family. This kinase functions as a mitogen-activated protein kinase (MAP kinase)- activated protein kinase. MAP kinases are also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This kinase was shown to be activated by growth inducers and stress stimulation of cells. In vitro studies demonstrated that ERK, p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase, which suggested the role of this kinase as an integrative element of signaling in both mitogen and stress responses. This kinase was reported to interact with, phosphorylate and repress the activity of E47, which is a basic helix-loop-helix transcription factor known to be involved in the regulation of tissue-specific gene expression and cell differentiation. [provided by RefSeq
  • Other Designations:
  • MAPKAP kinase 3
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