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PAK7 (Human) Recombinant ProteinBioActive

  • Catalog # : P4211
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  • Specification
  • Product Description:
  • Human PAK7 (Q9P286) full-length recombinant protein with GST expressed in Sf9 cells.
  • Host:
  • Insect
  • Theoretical MW (kDa):
  • 130
  • Form:
  • Liquid
  • Purity:
  • >= 75% by SDS-PAGE
  • Activity:
  • 55 nmol phosphate incorporated into the Akt substrate peptide (CKRPRAASFAE) per minute per mg protein at 30°C for 15 minutes using a final concentration of 50 uM ATP (0.83 uCi/assay).
  • Quality Control Testing:
  • 1 ug/lane SDS-PAGE Stained with Coomassie Blue

    QC Testing of P4211
  • Storage Buffer:
  • In 50 mM Tris-HCl, 150 mM NaCl, pH 7.5 (0.25 mM Dithiothreitol, 0.1 mM EGTA, 0.1 mM EDTA, 25% glycerol, 0.1 mM PMSF)
  • Storage Instruction:
  • Store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • Result of activity analysis

  • Applications
  • Functional Study
  • Application Image
  • Functional Study
  • Gene Information
  • Gene Name:
  • PAK7
  • Gene Alias:
  • KIAA1264,MGC26232,PAK5
  • Gene Description:
  • p21 protein (Cdc42/Rac)-activated kinase 7
  • Gene Summary:
  • The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. This kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000030258,OTTHUMP00000030259,OTTHUMP00000030260,p21(CDKN1A)-activated kinase 7,p21-activated kinase 7,protein kinase PAK5,serine/threonine-protein kinase PAK7
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